供应WHO09/182可溯源血管性血友病因子国际标准物质VWF

供应WHO09/182可溯源血管性血友病因子国际标准物质VWF

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The WHO 2nd International Standard (IS) for von Willebrand Factor,Concentrate was established by the Expert Committee on Biological Standardisation of the World Health Organisation in October 2010. The preparation consists of glass sealed ampoules (coded 09/182) containing 1 ml aliquots of von Willebrand factor concentrate, freeze-dried. The WHO 2nd IS is intended to be used for the estimation of von Willebrand factor in therapeutic concentrates via the calibration of working standards,such as manufacturers’ “in house” standards. The WHO 2nd IS has assigned values for the following analytes: WHO09/182

von Willebrand factor: antigen – VWF:Ag

von Willebrand factor: ristocetin cofactor – VWF:RCo

von Willebrand factor: collagen binding – VWF:CB

Further details on the preparation and the collaborative study can be found in the WHO document WHO/BS/10.2147.

This preparation is not for administration to humans or animals in the human food chain.The preparation contains material of human origin, and either the final product or the source materials, from which it is derived, have been tested and found negative for HBsAg, anti-HIV and HCV RNA. As with all materials of biological origin, this preparation should be regarded as potentially hazardous to health. It should be used and discarded according to your own laboratory’s safety procedures. Such safety procedures should include the wearing of protective gloves and avoiding the generation of aerosols. Care should be exercised in opening ampoules or vials, to avoid cuts. 可溯源血管性血友病因子国际标准物质VWF

世界卫生组织生物标准化专家委员会于2010年10月制定了von Willebrand因子浓缩物的第二个世界卫生组织国际标准(IS)。该制剂由玻璃密封安瓿(编号09/182)组成,安瓿中含有1毫升冷冻干燥的von Willebrand因子浓缩液。世界卫生组织第二信息系统旨在通过校准工作标准(例如制造商的“内部”标准)来估算治疗浓缩物中的冯·威莱布兰因子。世界卫生组织第二信息系统为以下分析物赋值:

血管性血友病因子:抗原-VWF:Ag

von Willebrand因子:ristocetin辅因子-VWF:RCo

血管性血友病因子:胶原结合-VWF:CB 该制剂不适用于人类或人类食物链中的动物。该制剂含有人类来源的物质,其最终产物或来源物质已经检测,HBsAg、抗-HIV和HCV RNA呈阴性。与所有生物来源的材料一样,这种制剂应被视为对健康有潜在危害。应根据您自己实验室的安全程序使用和丢弃它。此类安全程序应包括佩戴防护手套和避免产生气溶胶。打开安瓿或小瓶时应小心,以避免割伤。