| 名称 | Abacavir Sulfate |
|---|---|
| 英文名称 | Abacavir Sulfate |
| 中文名称 | 硫酸阿巴卡韦 |
| CAS号 | 188062-50-2 |
| 品牌 | DBN |
| 货号 | A987601 |
| 规格 | 10mg, 25mg, 50mg, 100mg |
| 储存温度 | -20°C Freezer, U17Under Inert Atmosphere |
| 货期 | 部分现货，详情请询 |
| 用途 | 仅供实验室使用 |
| 备注 | Abacavir Sulfate (Abacavir – In House Impurity) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. |
