N6-Cyclopropyl-9-[(1R,4S)-4-[(1,1-dimethylethoxy)methyl]-2-cyclopenten-1-yl]-9H-purine-2,6-diamine-d4

分类：其他, 化学试剂, 医药类标准品

其他信息

名称	N6-Cyclopropyl-9-[(1R, 4S)-4-[(1, 1-dimethylethoxy)methyl]-2-cyclopenten-1-yl]-9H-purine-2, 6-diamine-d4
英文名称	N6-Cyclopropyl-9-[(1R, 4S)-4-[(1, 1-dimethylethoxy)methyl]-2-cyclopenten-1-yl]-9H-purine-2, 6-diamine-d4
中文名称	N6-环丙基-9-[（1R，4S）-4-[（1, 1-二甲基乙氧基）甲基]-2-环戊烯-1-基]-9H-嘌呤-2, 6-二胺-d4
CAS号	NA
品牌	DBN
货号	A987637
规格	10mg, 25mg, 50mg, 100mg
储存温度	-20°C Freezer, U17Under Inert Atmosphere
货期	部分现货，详情请询
用途	仅供实验室使用
备注	2'-(R)-Hydroxy-2', 3'dihydroabacavir is the impurity of Abacavir (A104990). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.